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Review paper

Cord Blood Transplantation in Adult Patients With Hematological Malignancies

By
Goran Marjanović ,
Goran Marjanović
Milena Todorović-Bakrač ,
Milena Todorović-Bakrač
Tatjana Jevtović-Stoimenov
Tatjana Jevtović-Stoimenov

Abstract

The purpose of this review was to show the available clinical and biological advances of umbilical cord blood allogeneic stem cell transplantation in adult patients. In adults, umbilical cord blood transplantation, due to less pronounced graft versus host disease compared to conventional approaches may, be feasible in spite of slower engraftment. The authors discussed certain attempts for improvement of umbilical cord stem cells engraftment.   

References

1.
Brunstein GC, Barker JN, Weisdorf DJ, DeFor TE, Miller JS, BR B, et al. Umbilical cord blood transplan tation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematolo gic disease Blood 2007. 8(110):3064–70.

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