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A 64-year-old patient with extremely high number of white blood cells was diagnosed with T prolymphocytic leukemia. After the initiation of chemotherapy with Cyclophosphamide, Oncovin, Doxorubicin and Prednisone (CHOP), there was no improvement and the patient died within two months. Authors have made a review of the current therapy of this rare disorder of mature T-lymphocytes and discussed various therapeutic aspects of hyperlymphocytosis.
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