In vitro assessment of the lipid peroxidation of N,N'-disubstituted benzimidazole-2-thiones: Hydrazides vs esters
Introduction: Oxidative stress and resulting lipid peroxidation are involved in numerous pathological conditions. For this reason, the role of antioxidants attracts attention and the radical-scavenging capacity of many natural and synthetic supplements and drugs has been extensively evaluated. Material and methods: In the present study, seven N,N'-...
By Jelena Lazarević, Jelena Zvezdanović, Neda Anastassova, Anelia Mavrova, Denitsa Yancheva, Andrija Šmelcerović
Exercise training and inflammatory markers in coronary artery disease patients
Aim. To evaluate the influence of exercise training on inflammatory markers and exercise tolerance in coronary artery disease (CAD) patients. Patients and methods. A total of 54 subjects were enrolled in the present study, including 34 CAD patients (CAD group: 59.2 ± 8.2 years) and 20 healthy controls (C group: 54.2 ± 8.0 years). C reactive protein...
By Marina Deljanin-Ilić, Gordana Kocić, Gordana Lazarević, Dejan Simonović, Milovan Stojanović, Stevan Ilić, Branka Đorđević, Dejan Petrović, Sanja Stojanović
Pseudothrombocytopenia induced by ethylenediaminetetraacetic acid: A case report
Introduction: Pseudothrombocytopenia induced by ethylenediaminetetraacetic acid is a rare phenomenon caused by autoantibodies against platelet membrane with overall prevalence of 0.1% in the general population. This phenomenon is an in vitro artifact and with different anticoagulant used, the patient had the physiological platelet count. Case repor...
By Dejan Dobrijević, Nataša Kaćanski-Rađenović, Jasmina Katanić, Jovanka Kolarović
Formulation of biologics for alternative routes of administration: Current problems and perspectives
Introduction: Biologics (biopharmaceuticals) present new promising therapies for many diseases such as cancers, chronical inflammatory diseases and today's biggest challenge - COVID-19. Research: Today, most biologics have been synthetized using modern methods of biotechnology, in particular DNA recombinant technology. Current pharmaceutical forms ...
By Sanja Stanković, Marija Tasić-Kostov
The relationship between community noise and arterial hypertension in the population of the city of Niš
Aim: The aim of the study was to examine the relationship between noise exposure and the incidence of arterial hypertension as well as the relationship of noise annoyance and noise sensitivity with hypertension. Methods: A cross-sectional questionnaire survey was performed on 911 adult residents of Niš, Serbia, of whom 388 were men (42.6%) and 523 ...
By Ljiljana Stošić, Dušica Stojanović, Konstansa Lazarević
Application of machine learning in the fight against the COVID-19 pandemic: A review
Introduction: Machine learning (ML) plays a significant role in the fight against the COVID-19 (officially known as SARS-CoV-2) pandemic. ML techniques enable the rapid detection of patterns and trends in large datasets. Therefore, ML provides efficient methods to generate knowledge from structured and unstructured data. This potential is particula...
By Alem Čolaković, Elma Avdagić-Golub, Muhamed Begović, Belma Memić, Adisa Hasković-Džubur
The relationship between neutrophil-lymphocyte ratio and clinal laboratory data in acute pancreatitis
Introduction: Neutrophil-lymphocyte ratio (NLR) is one of the laboratory biomarkers used in clinical practice to predict severity and mortality of acute pancreatitis (AP), however, there is currently insufficient information about the changes of NLR in the dynamics in relationship with other clinical and laboratory data. Aims: To assess the relatio...
By Tetiana Formanchuk, Hryhoriy Lapshyn, Mariya Pokidko, Andrii Formanchuk, Igor Vovchuk
The impact of the COVID-19 pandemic on the quality of life of laryngectomized patients
Introduction: Quality of life is a state of complete physical, mental and social well-being. Due to the COVID-19 pandemic, which led to changes in the daily routine, there was a change in the psychosocial functioning of individuals. Given that laryngectomized patients belong to a vulnerable group that requires psychological support after surgery, s...
By Mirjana Petrović-Lazić, Snežana Babac, Ivana Ilić-Savić
Neurological and psychiatric comorbidities in bullous pemphigoid
Introduction: Bullous pemphigoid (BP) is an autoimmune skin disease that typically presents with severe itching and blistering, with or without eczematous and urticarial lesions. Patients with BP are at an increased risk of comorbid conditions, especially neurologic and psychiatric diseases. Several recent studies have found a link between BP and n...
By Arsovska Mirceska, Katerina Damevska, Viktor Simeonovski, Andrija Jović, Danica Tiodorović
Could nucleolin and nucleophosmin levels be prognostic indicators in non-small cell lung cancer?
Aim: Lung cancer is the leading cause of mortality from cancer across the world. In this study, the use of serum nucleolin (NCL) and nucleophosmin (NPM1) levels as a marker in the diagnosis, prognosis and treatment response evaluation in lung cancer was investigated. Materials and Method: NCL and NPM1 levels of serum samples taken before chemothera...
By Gül Akın, Onur Esbah, Recep Eröz